The ability to collect spatial and chemical information can give great insights into a range of samples from disease signatures in tissue to aging in varnishes and pigments used in frescoes. On the Multimode InfraRed Imaging And Microspectroscopy (MIRIAM) beamline (B22) the broadband infrared (IR) radiation obtained from the synchrotron is used to collect high quality spectra with better spatial resolution than is possible from a thermal IR source. At the moment these chemical maps are measured point-by-point and can take hours to collect. Advances in IR detection now allows chemical images to be collected all in one go. On B22 we are investigating how to exploit this new detector technology with the synchrotron radiation IR (SRIR) to offer chemical imaging experiments not possible with other IR sources.
To find out more about the B22 beamline, or to discuss potential applications, please contact Principal Beamline Scientists Dr Gianfelice Cinque: [email protected]
1. Quaroni. L, et al. Synchrotron based IR imaging and spectroscopy via FPA on live fibroblasts in D2O medium, Biophys. Chem. 189, 40 (2014)
2. Quaroni. L, Zlateva. T, et al. Infrared imaging of small molecules in living cells: from in vitro metabolic analysis to cytopathology, Faraday Discussion, 187, 259 (2016)
3. Hirschmugl. C, Gough. K, Fourier Transform Infrared Spectrochemical Imaging: Review of Design and Applications with a Focal Plane Array and Multiple Beam Synchrotron Radiation Source, Applied Spec, 66, 5 (2012)
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