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Industrial Liaison Group:
Tel: +44 (0) 1235 778797
E-mail: industry@diamond.ac.uk
We hope that this newsletter will help to keep you up to date with the very latest developments, updates and events on our structural biology beamlines. If you have any ideas or suggestions for events that you would find interesting or useful, please do let us know at industry@diamond.ac.uk
Membrane Protein Lab
The Membrane Protein Laboratory (MPL) at Diamond Light Source is a research and training user facility open to scientists from laboratories anywhere in the world that are interested in Structural Biology of Membrane Proteins. The laboratory combines recently developed high throughput technologies for protein production and crystallisation with the latest developments in X-ray diffraction data collection systems at Diamond MX beamlines. Read more here...
eBIC
The Electron Bio-Imaging Centre (eBIC) was established at Diamond following the award of a £15.6 million grant from the Wellcome Trust, the Medical Research Council (MRC) and the Biotechnology and Biological Sciences Research Council (BBSRC). Currently eBIC houses four Titan Krios microscopes, a Talos Arctica and a Scios cryo-FIB/SEM. The Polara microscope is located at the University of Oxford. Read more here...
PanDDA
“The problem of identifying binding events in crystallographic datasets can feel like looking for a needle in a haystack.” Scientists have utilised Diamond Light Source to develop a new method to extract previously hidden information from the X-ray diffraction data that are measured when resolving the three-dimensional (3D) atomic structures of proteins and other biological molecules. Read more here....
VMXi
Princess Anne unveils Diamond's newest addition to the structural biology suite; a new Versatile Macromolecular crystallography in situ (VMXi) beamline – currently the only one of its kind worldwide. Read more here....
Technology Updates
Boosting Beamline B21
Beamline B21 is dedicated to solution state protein SAXS that can accommodate a wide variety of aqueous-based and some limited organic solvent-based samples. It has had a recent upgrade which has boosted its data collecting abilities (up to 60 times faster data collection). Read about the beamline, the upgrade and the furture developments here....
Puck barcoding and pucks scan-recognition at MX beamlines
From April 2017, we will be etching barcodes to all unipucks that come to the MX beamlines. The barcode duplicates the existing puck ID in a 2D format and will be used for tracking of the puck positions in the sample changer.
Updates to Beamline I04
The I04 beamline installed a new SmarGon for faster and precise sample centering and data collection with multi-axis goniometer functionality. In addition, recent beamline upgrades provide a much faster way to change energy and beamsize.
Fast Grid Scans on I24
Grid scans have now been sped up by almost an order of magnitude using an approach developed from the one we use here at Diamond for fixed target serial crystallography Sherrell et al. J. Synch Rad (2015), Owen et al. Acta Cryst D (2017) in press.
Campus Updates
Find out about the exciting news from the campus including the new Rosalind Franklin Institute and the newly appointed head of the Research Complex at Harwell (RCaH)
Techniques Available for Structural Biology
We’re always happy to discuss any enquiries or talk about ways in which access to Diamond’s facilities may be beneficial to your business so please do give us a call on 01235 778797 or send us an e-mail. You can keep in touch with the latest development by following us on Twitter @DiamondILO or LinkedIn
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Industrial Liaison Office
