11 February 2013, The Winchester Hotel
Diamond Light Source – University of Southampton
09:30 Registration
09:55 Welcome note
10:00 B23 overview and update
10:30 CD Spectroscopy as a tool to analyse modified DNA
Eugen Stulz, Southampton University
11:00 Exploring the role of lipid/protein interactions in cellular processes by circular dichroism
Phil Williamson, Southampton University
11:30 Coffee/Tea break
12:00 DNA-response regulator protein interactions: insights into the DNA binding specificity of the effector domain of the global regulator PrrA (RegA) from Rhodobacter sphaeroides PrrA
Mary Phillips-Jones, University of Central Lancashire
12:30 Unpair to Repair at DNA and RNA Duplex Termini
David Finger, Sheffield University
13:00 Lunch
14:00 Using CD to investigate the role of nucleic acid structure in gene regulation
Garry Scarlett, Portsmouth University
14:30 Probing DNA conformation and DNA-enzyme interaction using time-resolved fluorescence
Anita Jones, Edinburgh University
15:00 Use of the 3’-S phosphorothiolate substitution to modify DNA structure, as determined
by NMR spectroscopy and UV thermal melting studies
Julie Fisher, University of Leeds
15:30 Coffee break
16:00 Synthesis and Study of Modified Photochromic and Organometallic nucleic acids
Jim Tucker, Birmingham University
16:30 Feedback and Discussion
17:00 End of Workshop