I am interested in the interfacial behaviour of a range of species from simple molecules to surfactants and more complex lipid & protein systems. Such systems are important to many areas of academic, medical and industrial importance and are well suited to the techniques available on I07. Using simplified systems and a combination of different techniques it is possible to obtain detailed information that can help us to understand the fundamental properties that govern behaviour.
One of my areas of research focuses on Styrene Maleic Acid Lipid Particles (SMALPs)
and their interaction with surfaces. These particles provide a relatively new method to extract and purify Membrane Proteins, along with the local lipid bilayer proximal to the protein. Once solubilized in SMALPs, proteins can be studied in a variety of ways. My work has focussed on using a wide range of experimental techniques, particularly x-ray and neutron scattering, to investigate their physical properties and their interactions with and/or binding to surfaces.
Other projects include:
- Use of a range of techniques to study the structure and dynamics of physisorbed molecules.
- The behaviour of surfactants & lipids in ionic liquids & deep eutectic solvents.
- Structural studies and characterisation of lipids, proteins and new & novel surfactants at different surfaces including air-liquid, liquid-liquid and solid-liquid interfaces.
On the beamline I principally provide support for users working in soft-matter research, with particular responsiblity for reflectometry and studies at liquid surfaces.